• Biotinylated Human TRAIL R4 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
  • The purity of Biotinylated Human TRAIL R4 is greater than 95% as determined by SEC-HPLC.
  • Immobilized Human TRAIL, No Tag at 5 Mu g/ml (100 Mu l/well) on the plate. Dose response curve for Biotinylated Human TRAIL R4, His Tag with the EC50 of 0. 14 Mu g/ml determined by ELISA.
  • Biotinylated Human TRAIL R4, His-Avi Tag immobilized on CM5 Chip can bind Human TRAIL, No Tag with an affinity constant of 0. 135 nM as determined in SPR assay (Biacore T200).

Human TRAIL R4/TNFRSF10D protein (Recombinant) (C-His-Avi) {Biotin} (STJP001719)

SKU:
STJP001719

£597.50 - £1,839.50
Shipping:
Free Shipping
Current Stock:
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human TRAIL R4/TNFRSF10D-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: TNFRSF10D
Gene ID: 8793
Uniprot ID: TR10D_HUMAN
Immunogen Region: Ala56-His211
Immunogen: DNA sequence encoding Human TRAIL R4/TNFRSF10D including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. it cannot but it can induce the NF-kappa-B pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 10d
Decoy Receptor 2
Dcr2
Tnf-Related Apoptosis-Inducing Ligand Receptor 4
Trail Receptor 4
Trail-R4
Trail Receptor With A Truncated Death Domain
Cd Antigen Cd264
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6803211
Reactome: R-HSA-75158
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 10d protein
Decoy Receptor 2 protein
Dcr2 protein
Tnf-Related Apoptosis-Inducing Ligand Receptor 4 protein
Trail Receptor 4 protein
Trail-R4 protein
Trail Receptor With A Truncated Death Domain protein
Cd Antigen Cd264 protein
TNFRSF10D protein
DCR2 protein
TRAILR4 protein
TRUNDD protein
UNQ251 protein
PRO288 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance