Human TOMM20 protein (Recombinant) (His-Tag) (STJP018219)

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STJP018219
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TOMM20-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 2mM DTT
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: TOMM20
Gene ID: 9804
Uniprot ID: TOM20_HUMAN
Immunogen Region: 25-145aa
Accession Number: NP_055580
Immunogen: Human
Immunogen Sequence: DRKRRSD PNFKNRLRER RKKQKLAKER AGLSKLPDLK DAEAVQKFFL EEIQLGEELL AQGEYEKGVD HLTNAIAVCG QPQQLLQVLQ QTLPPPVFQM LLTKLPTISQ RIVSAQSLAE DDVE
Post Translational Modifications Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
Function Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
Protein Name Mitochondrial Import Receptor Subunit Tom20 Homolog
Mitochondrial 20 Kda Outer Membrane Protein
Outer Mitochondrial Membrane Receptor Tom20
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-5205685
Reactome: R-HSA-5689880
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Alternative Protein Names Mitochondrial Import Receptor Subunit Tom20 Homolog protein
Mitochondrial 20 Kda Outer Membrane Protein protein
Outer Mitochondrial Membrane Receptor Tom20 protein
TOMM20 protein
KIAA0016 protein

Information sourced from Uniprot.org

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