Human TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily Member 1a) Antibody Pair (STJAP00200)

SKU:
STJAP00200-50
£499.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mouse/Goat
Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This TNFRSF1A antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Monoclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Protein A or G.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: TNFRSF1A
Gene ID: 7132
Uniprot ID: TNR1A_HUMAN
Immunogen: Capture immunogen: Recombinant Human TNFRSF1A protein.
Detection Immunogen: Recombinant Human TNFRSF1A protein.
Function Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 1a
Tumor Necrosis Factor Receptor 1
Tnf-R1
Tumor Necrosis Factor Receptor Type I
Tnf-Ri
Tnfr-I
P55
P60
Cd Antigen Cd120a Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1a - Membrane Form - Tumor Necrosis Factor-Binding Protein 1
Tbpi
Database Links Reactome: R-HSA-5357786
Reactome: R-HSA-5357905
Reactome: R-HSA-5357956
Reactome: R-HSA-5626978
Reactome: R-HSA-5669034
Reactome: R-HSA-6783783
Reactome: R-HSA-75893
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Golgi Apparatus Membrane
Secreted
A Secreted Form Is Produced Through Proteolytic Processing
Isoform 4: Secreted
Lacks A Golgi-Retention Motif
Is Not Membrane Bound And Therefore Is Secreted
Alternative Antibody Pair Names Tumor Necrosis Factor Receptor Superfamily Member 1a antibody pair
Tumor Necrosis Factor Receptor 1 antibody pair
Tnf-R1 antibody pair
Tumor Necrosis Factor Receptor Type I antibody pair
Tnf-Ri antibody pair
Tnfr-I antibody pair
P55 antibody pair
P60 antibody pair
Cd Antigen Cd120a Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1a - Membrane Form - Tumor Necrosis Factor-Binding Protein 1 antibody pair
Tbpi antibody pair
TNFRSF1A antibody pair
TNFAR antibody pair
TNFR1 antibody pair

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0002062 Human TNFRSF1A (Tumor necrosis factor receptor superfamily member 1A) Sandwich ELISA Kit (STJE0002062) Human ELISA
STJE0019774 Mouse TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A) Sandwich ELISA Kit (STJE0019774) Mouse ELISA
STJAP00382 Human TNFRSF9 (Tumor Necrosis Factor Receptor Superfamily Member 9) Antibody Pair (STJAP00382) Goat/Goat Human ELISA
STJAP00210 Human TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily Member 1b) Antibody Pair (STJAP00210) Mouse/Goat Monoclonal/Polyclonal Human ELISA
STJAP00054 Human OPG (Tumor Necrosis Factor Receptor Superfamily Member 11b) Antibody Pair (STJAP00054) Mouse/Goat Monoclonal/Polyclonal Human ELISA
!