Human TMED1 protein (Recombinant) (C-Fc) (STJP013449)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TMED1-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | TMED1 |
| Gene ID | 11018 |
| Uniprot ID | TMED1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala24-Asn194 |
Additional Info
| Function | Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1. Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. |
| Protein Name | Transmembrane Emp24 Domain-Containing Protein 1Interleukin-1 Receptor-Like 1 LigandPutative T1/St2 Receptor-Binding ProteinP24 Family Protein Gamma-1Tp24P24gamma1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum MembraneGolgi ApparatusCis-Golgi Network MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment Membrane |
| Alternative Protein Names | Transmembrane Emp24 Domain-Containing Protein 1 proteinInterleukin-1 Receptor-Like 1 Ligand proteinPutative T1/St2 Receptor-Binding Protein proteinP24 Family Protein Gamma-1 proteinTp24 proteinP24gamma1 proteinTMED1 proteinIL1RL1L proteinIL1RL1LG protein |
Information sourced from Uniprot.org