Human TMED1 protein (Recombinant) (C-Fc) (STJP013449)

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STJP013449-100
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Short Description :Recombinant-Human TMED1-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:TMED1
Gene ID:11018
Uniprot ID:TMED1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ala24-Asn194
Function Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1. Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.
Protein Name Transmembrane Emp24 Domain-Containing Protein 1
Interleukin-1 Receptor-Like 1 Ligand
Putative T1/St2 Receptor-Binding Protein
P24 Family Protein Gamma-1
Tp24
P24gamma1
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cis-Golgi Network Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Alternative Protein Names Transmembrane Emp24 Domain-Containing Protein 1 protein
Interleukin-1 Receptor-Like 1 Ligand protein
Putative T1/St2 Receptor-Binding Protein protein
P24 Family Protein Gamma-1 protein
Tp24 protein
P24gamma1 protein
TMED1 protein
IL1RL1L protein
IL1RL1LG protein

Information sourced from Uniprot.org