Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. |
Protein Name | Metalloproteinase Inhibitor 2Csc-21kTissue Inhibitor Of Metalloproteinases 2Timp-2 |
Database Links | Reactome: R-HSA-1592389Reactome: R-HSA-6798695Reactome: R-HSA-9839383 |
Cellular Localisation | Secreted |
Alternative Protein Names | Metalloproteinase Inhibitor 2 proteinCsc-21k proteinTissue Inhibitor Of Metalloproteinases 2 proteinTimp-2 proteinTIMP2 protein |
Information sourced from Uniprot.org