Human THSD7A (Thrombospondin Type I Domain Containing Protein 7A) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018954)
SPECIFICATIONS
General Information
| Short Description | This THSD7A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.058ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | THSD7A |
| Gene ID | 221981 |
| Uniprot ID | THS7A_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected on kidney podocytes along the glomerular capillary wall (at protein level). |
| Post Translational Modifications | Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form. Extensively N-glycosylated. |
| Function | Thrombospondin type-1 domain-containing protein 7A: Plays a role in actin cytoskeleton rearrangement. Thrombospondin type-1 domain-containing protein 7A, soluble form: The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism. |
| Protein Name | Thrombospondin Type-1 Domain-Containing Protein 7a Cleaved Into - Thrombospondin Type-1 Domain-Containing Protein 7a - Soluble Form |
| Database Links | Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | Thrombospondin Type-1 Domain-Containing Protein 7a: Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionDetected On Podocyte Foot ProcessesThrombospondin Type-1 Domain-Containing Protein 7aSoluble Form: SecretedProteolytic Cleavage In The Extracellular Region Generates A 210 Kda Soluble Form |
| Alternative ELISA Names | Thrombospondin Type-1 Domain-Containing Protein 7a Cleaved Into - Thrombospondin Type-1 Domain-Containing Protein 7a - Soluble Form ELISA kitTHSD7A ELISA kitKIAA0960 ELISA kit |
| output |
Information sourced from Uniprot.org