| Host: | E.coli |
| Applications: | Enzyme Activity/SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Thioredoxin-2-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Specific activity is >40 A650/cm/min/mg, obtained by measuring the increase of insulin precipitation in absorbance at 650 nm resulting from the reduction of insulin. |
| Gene Symbol: | TXN2 |
| Gene ID: | 25828 |
| Uniprot ID: | THIOM_HUMAN |
| Immunogen Region: | 60-166aa |
| Accession Number: | NP_036605 |
| Immunogen: | Human |
| Immunogen Sequence: | MTTFNIQDGP DFQDRVVNSE TPVVVDFHAQ WCGPCKILGP RLEKMVAKQH GKVVMAKVDI DDHTDLAIEY EVSAVPTVLA MKNGDVVDKF VGIKDEDQLE AFLKKLIG |
| Tissue Specificity | Widely expressed in adult (at protein level) and fetal tissues. |
| Function | Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability Is involved in various redox reactions including the reduction of protein disulfide bonds, through the reversible oxidation of its active center dithiol to a disulfide. |
| Protein Name | Thioredoxin - MitochondrialMtrxMt-TrxThioredoxin-2 |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-3299685 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Thioredoxin - Mitochondrial proteinMtrx proteinMt-Trx proteinThioredoxin-2 proteinTXN2 proteinTRX2 protein |
Information sourced from Uniprot.org