| Short Description : | Recombinant-Active-Human TFPI2-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, McaRPKPVE-NvalWRK (Dnp)-NH2. The IC50 value is <5 nM, as measured under the described conditions. |
| Gene Symbol: | TFPI2 |
| Gene ID: | 7980 |
| Uniprot ID: | TFPI2_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Asp23-Lys213 |
| Function | May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. |
| Protein Name | Tissue Factor Pathway Inhibitor 2Tfpi-2Placental Protein 5Pp5 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Tissue Factor Pathway Inhibitor 2 proteinTfpi-2 proteinPlacental Protein 5 proteinPp5 proteinTFPI2 protein |
Information sourced from Uniprot.org