| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value approximately is 1.7 nM. |
| Gene Symbol: | SPOCK1 |
| Gene ID: | 6695 |
| Uniprot ID: | TICN1_HUMAN |
| Immunogen Region: | Arg22-Trp439 |
| Immunogen: | Recombinant Human Testican-1/SPOCK1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Arg22-Trp439) of human Testican 1/SPOCK1 (Accession #NP_004589.1.) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | RHLDALAGGAGPNHGNFLDN DQWLSTVSQYDRDKYWNRFR DDDYFRNWNPNKPFDQALDP SKDPCLKVKCSPHKVCVTQ DYQTALCVSRKHLLPRQKKG NVAQKHWVGPSNLVKCKPCP V AQSAMVCGSDGHSYTSKC KLEFHACSTGKSLATLCDGP CPCLPEPEPPKHKAERSACT DK ELRNLASRLKDWFGALH EDANRVIKPTSSNTAQGRFD TSILPICKDSLGWMFNKLDM |
| Function | May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system. |
| Protein Name | Testican-1Protein Spock |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Testican-1 proteinProtein Spock proteinSPOCK1 proteinSPOCK proteinTIC1 proteinTICN1 protein |
Information sourced from Uniprot.org
