Function | Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription. Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'. |
Protein Name | Transcription Factor 4Tcf-4Class B Basic Helix-Loop-Helix Protein 19Bhlhb19Immunoglobulin Transcription Factor 2Itf-2Sl3-3 Enhancer Factor 2Sef-2 |
Database Links | Reactome: R-HSA-525793Reactome: R-HSA-9839394 |
Cellular Localisation | Nucleus |
Alternative Protein Names | Transcription Factor 4 proteinTcf-4 proteinClass B Basic Helix-Loop-Helix Protein 19 proteinBhlhb19 proteinImmunoglobulin Transcription Factor 2 proteinItf-2 proteinSl3-3 Enhancer Factor 2 proteinSef-2 proteinTCF4 proteinBHLHB19 proteinITF2 proteinSEF2 protein |
Information sourced from Uniprot.org