Human TCF4 protein (Recombinant) (N-GST & C-His) (STJP007525)

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STJP007525
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TCF4-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TCF4
Gene ID: 6925
Uniprot ID: ITF2_HUMAN
Immunogen Region: Asp552-Ala631
Immunogen: Homo sapiens (Human)
Function Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription. Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.
Protein Name Transcription Factor 4
Tcf-4
Class B Basic Helix-Loop-Helix Protein 19
Bhlhb19
Immunoglobulin Transcription Factor 2
Itf-2
Sl3-3 Enhancer Factor 2
Sef-2
Database Links Reactome: R-HSA-525793
Reactome: R-HSA-9839394
Cellular Localisation Nucleus
Alternative Protein Names Transcription Factor 4 protein
Tcf-4 protein
Class B Basic Helix-Loop-Helix Protein 19 protein
Bhlhb19 protein
Immunoglobulin Transcription Factor 2 protein
Itf-2 protein
Sl3-3 Enhancer Factor 2 protein
Sef-2 protein
TCF4 protein
BHLHB19 protein
ITF2 protein
SEF2 protein

Information sourced from Uniprot.org

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