Name: Human Syntaxin 4 protein (Recombinant) (His-Tag) (STJP017776)
SKU: STJP017776
Availability: InStock

Human Syntaxin 4 protein (Recombinant) (His-Tag) (STJP017776)

SKU:

STJP017776

£134.50 - £738.50

Short Description :	Recombinant-Human Syntaxin 4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	1 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% Glycerol, 1mM DTT
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol:	STX4
Gene ID:	6810
Uniprot ID:	STX4_HUMAN
Accession Number:	NP_004595
Immunogen:	Human
Immunogen Region:	1-275aa
Immunogen Sequence:	MGSSHHHHHH SSGLVPRGSH MGSHMMRDRT HELRQGDDSS DEEDKERVAL VVHPGTARLG SPDEEFFHKV RTIRQTIVKL GNKVQELEKQ QVTILATPLP EESMKQELQN LRDEIKQLGR EIRLQLKAIE PQKEEADENY NSVNTRMRKT QHGVLSQQFV ELINKCNSMQ SEYREKNVER IRRQLKITNA GMVSDEELEQ MLDSGQSEVF VSNILKDTQV TRQALNEI

Tissue Specificity	Expressed in neutrophils and neutrophil-differentiated HL-60 cells. Expression in neutrophils increases with differentiation.
Function	Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. In neurons, recruited at neurite tips to membrane domains rich in the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) which promotes neurite tip surface expression of the dopamine transporter SLC6A3/DAT by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones. Required for normal hearing.
Protein Name	Syntaxin-4 Renal Carcinoma Antigen Ny-Ren-31
Database Links	Reactome: R-HSA-114516 Reactome: R-HSA-1236974 Reactome: R-HSA-1445148 Reactome: R-HSA-199992 Reactome: R-HSA-449836
Cellular Localisation	Cell Membrane Single-Pass Type Iv Membrane Protein Cell Projection Neuron Projection Stereocilium Localizes To Neurite Tips In Neuronal Cells
Alternative Protein Names	Syntaxin-4 protein Renal Carcinoma Antigen Ny-Ren-31 protein STX4 protein STX4A protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP017663	Human Syntaxin 11 protein (Recombinant) (His-Tag) (STJP017663)	E.coli	SDS-PAGE/Denatured
STJP017647	Human Syntaxin 12 protein (Recombinant) (His-Tag) (STJP017647)	E.coli	SDS-PAGE
STJP018447	Human Syntaxin 17 protein (Recombinant) (His-Tag) (STJP018447)	E.coli	SDS-PAGE
STJP018446	Human Syntaxin 6 protein (Recombinant) (His-Tag) (STJP018446)	E.coli	SDS-PAGE
STJP017618	Human Syntaxin 3 protein (Recombinant) (His-Tag) (STJP017618)	E.coli	SDS-PAGE

Human Syntaxin 4 protein (Recombinant) (His-Tag) (STJP017776)

General Information