Human Syntaxin 3 protein (Recombinant) (His-Tag) (STJP017618)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Syntaxin 3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% Glycerol, 100mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STX3 |
| Gene ID | 6809 |
| Uniprot ID | STX3_HUMAN |
| Accession Number | NP_004168 |
| Immunogen | Human |
| Immunogen Region | 1-263aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Isoform A: Expressed in small intestine, kidney, pancreas, placenta as well as in retina. Weaker expression in lung, liver and heart. Not expressed in brain and skeletal muscle. Isoform B: Expressed only in the retina. Isoform 3: Ubiquitously expressed. |
| Function | Potentially involved in docking of synaptic vesicles at presynaptic active zones. Apical receptor involved in membrane fusion of apical vesicles. Isoform B: Essential for survival of retinal photoreceetors. Isoform 3: Functions as a regulator of gene expression. |
| Protein Name | Syntaxin-3 |
| Database Links | Reactome: R-HSA-449836 |
| Cellular Localisation | Isoform A: Apical Cell MembraneSingle-Pass Type Iv Membrane ProteinLocalized To The Inner And Outer Plexiform LayersThe Cell Body And The Inner Segments Of PhotoreceptorsIsoform 3: Nucleus |
| Alternative Protein Names | Syntaxin-3 proteinSTX3 proteinSTX3A protein |
Information sourced from Uniprot.org