| Short Description : | Recombinant-Human Syntaxin 12-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STX12 |
| Gene ID: | 23673 |
| Uniprot ID: | STX12_HUMAN |
| Accession Number: | NP_803173.1 |
| Immunogen: | Human |
| Immunogen Region: | 1-248aa |
| Immunogen Sequence: |
| Function | SNARE promoting fusion of transport vesicles with target membranes. Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting. |
| Protein Name | Syntaxin-12 |
| Database Links | |
| Cellular Localisation | Endosome MembraneSingle-Pass Type Iv Membrane ProteinGolgi Apparatus MembraneEndomembrane SystemCytoplasmic SideEarly Endosome MembraneRecycling Endosome Membrane |
| Alternative Protein Names | Syntaxin-12 proteinSTX12 protein |
Information sourced from Uniprot.org