Name: Human Sulfotransferase 1E1/SULT1E1 protein (Recombinant) (His-Tag) (STJP016433)
SKU: STJP016433
Availability: InStock

Human Sulfotransferase 1E1/SULT1E1 protein (Recombinant) (His-Tag) (STJP016433)

SKU:

STJP016433

$185.61 - $1,019.13

Short Description :	Recombinant-Human Sulfotransferase 1E1/SULT1E1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	1 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin:	< 1 EU per 1ug of protein (determined by LAL method)

Gene Symbol:	SULT1E1
Gene ID:	6783
Uniprot ID:	ST1E1_HUMAN
Accession Number:	AAH27956.1
Immunogen:	Human
Immunogen Region:	1-294aa
Immunogen Sequence:	MNSELDYYEK FEEVHGILMY KDFVKYWDNV EAFQARPDDL VIATYPKSGT TWVSEIVYMI YKEGDVEKCK EDVIFNRIPF LECRKENLMN GVKQLDEMNS PRIVKTHLPP ELLPASFWEK DCKIIYLCRN AKDVAVSFYY FFLMVAGHPN PGSLPEFVEK FMQGQVPYGS WYKHVKSWWE KGKSPRVLFL FYEDLKEDIR KEVIKLIHFL ERKPSEELVD RIIHHTSF

Tissue Specificity	Liver, intestine and at lower level in the kidney.
Function	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. Is a key enzyme in estrogen homeostasis, the sulfation of estrogens leads to their inactivation. Also sulfates dehydroepiandrosterone (DHEA), pregnenolone, (24S)-hydroxycholesterol and xenobiotic compounds like ethinylestradiol, equalenin, diethyl stilbesterol and 1-naphthol at significantly lower efficiency. Does not sulfonate cortisol, testosterone and dopamine. May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system.
Protein Name	Sulfotransferase 1e1 St1e1 Est-1 Estrogen Sulfotransferase Sulfotransferase - Estrogen-Preferring
Database Links	Reactome: R-HSA-156584 Reactome: R-HSA-9753281
Cellular Localisation	Cytoplasm Cytosol
Alternative Protein Names	Sulfotransferase 1e1 protein St1e1 protein Est-1 protein Estrogen Sulfotransferase protein Sulfotransferase - Estrogen-Preferring protein SULT1E1 protein STE protein

Information sourced from Uniprot.org

Human Sulfotransferase 1E1/SULT1E1 protein (Recombinant) (His-Tag) (STJP016433)

General Information

Model	Name	Host	Application
STJP016978	Human Sulfotransferase 1C2/SULT1C2 protein (Recombinant) (His-Tag) (STJP016978)	E.coli	SDS-PAGE
STJP017218	Human Sulfotransferase 2A1/SULT2A1 protein (Recombinant) (His-Tag) (STJP017218)	E.coli	SDS-PAGE
STJP017270	Human Sulfotransferase 1A2/SULT1A2 protein (Recombinant) (His-Tag) (STJP017270)	E.coli	SDS-PAGE
STJP017648	Human Sulfotransferase 1B1/SULT1B1 protein (Recombinant) (His-Tag) (STJP017648)	E.coli	SDS-PAGE
STJP018217	Human Sulfotransferase 1C4/SULT1C4 protein (Recombinant) (His-Tag) (STJP018217)	E.coli	SDS-PAGE