SULT1B1 recombinant protein SDS-PAGE gel 3 µg Coomassie stain reducing conditions

Human Sulfotransferase 1B1/SULT1B1 protein (Recombinant) (His-Tag) (STJP017648)

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STJP017648
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Short Description :Recombinant-Human Sulfotransferase 1B1/SULT1B1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:SULT1B1
Gene ID:27284
Uniprot ID:ST1B1_HUMAN
Accession Number:NP_055280
Immunogen:Human
Immunogen Region:1-296aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMLSPKD ILRKDLKLVH GYPMTCAFAS NWEKIEQFHS RPDDIVIATY PKSGTTWVSE IIDMILNDGD IEKCKRGFIT EKVPMLEMTL PGLRTSGIEQ LEKNPSPRIV KTHLPTDLLP KSFWENNCKM IYLARNAKDV SVSYYHFDLM NNLQPFPGTW EEYLEKFLTG KVAYGSWFTH VKNWWKKKEE HPILFLYYED MKENPKEE
Tissue Specificity Highly expressed in the liver, peripheral blood leukocytes, colon (mucosal lining), small intestine (jejunum) and spleen. A lesser expression was observed in the lung, placenta and thymus.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3). May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system.
Protein Name Sulfotransferase 1b1
St1b1
Sulfotransferase 1b2
Sulfotransferase Family Cytosolic 1b Member 1
Thyroid Hormone Sulfotransferase
Database Links Reactome: R-HSA-156584
Cellular Localisation Cytoplasm
Alternative Protein Names Sulfotransferase 1b1 protein
St1b1 protein
Sulfotransferase 1b2 protein
Sulfotransferase Family Cytosolic 1b Member 1 protein
Thyroid Hormone Sulfotransferase protein
SULT1B1 protein
ST1B2 protein
SULT1B2 protein

Information sourced from Uniprot.org

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