| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human SPINT2-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | SPINT2 |
| Gene ID: | 10653 |
| Uniprot ID: | SPIT2_HUMAN |
| Immunogen Region: | Met1-Lys197 |
| Immunogen: | Homo sapiens (Human) |
| Function | Inhibitor of HGFAC. Also inhibits plasmin, and plasma and tissue kallikrein. Inhibits serine protease activity of TMPRSS13. Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro. |
| Protein Name | Kunitz-Type Protease Inhibitor 2Hepatocyte Growth Factor Activator Inhibitor Type 2Hai-2Placental Bikunin |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
| Alternative Protein Names | Kunitz-Type Protease Inhibitor 2 proteinHepatocyte Growth Factor Activator Inhibitor Type 2 proteinHai-2 proteinPlacental Bikunin proteinSPINT2 proteinHAI2 proteinKOP protein |
Information sourced from Uniprot.org