SDS-PAGE gel of recombinant human SNTA1 protein stained with Coomassie blue

Human SNTA1 protein (Recombinant) (His-Tag) (STJP017485)

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STJP017485
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Short Description :Recombinant-Human SNTA1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.15M NaCl.
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:SNTA1
Gene ID:6640
Uniprot ID:SNTA1_HUMAN
Accession Number:NP_003089.1
Immunogen:Human
Immunogen Region:1-505aa
Immunogen Sequence:MASGRRA PRTGLLELRA GAGSGAGGER WQRVLLSLAE DVLTVSPADG DPGPEPGAPR EQEPAQLNGA AEPGAGPPQL PEALLLQRRR VTVRKADAGG LGISIKGGRE NKMPILISKI FKGLAADQTE ALFVGDAILS VNGEDLSSAT HDEAVQVLKK TGKEVVLEVK YMKDVSPYFK NSTGGTSVGW DSPPASPLQR QPSSPG
Tissue Specificity High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta.
Post Translational Modifications Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD.
Function Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate.
Protein Name Alpha-1-Syntrophin
59 Kda Dystrophin-Associated Protein A1 Acidic Component 1
Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1
Tacip1
Syntrophin-1
Database Links Reactome: R-HSA-9913351
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cytoplasmic Side
Cell Junction
Cytoplasm
Cytoskeleton
In Skeletal Muscle
It Localizes At The Cytoplasmic Side Of The Sarcolemmal Membrane And At Neuromuscular Junctions
Alternative Protein Names Alpha-1-Syntrophin protein
59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 protein
Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 protein
Tacip1 protein
Syntrophin-1 protein
SNTA1 protein
SNT1 protein

Information sourced from Uniprot.org

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