Post Translational Modifications | Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases. |
Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. |
Protein Name | Gamma-SynucleinBreast Cancer-Specific Gene 1 ProteinPersynSynoretinSr |
Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleAssociated With Centrosomes In Several Interphase CellsIn Mitotic CellsLocalized To The Poles Of The Spindle |
Alternative Protein Names | Gamma-Synuclein proteinBreast Cancer-Specific Gene 1 Protein proteinPersyn proteinSynoretin proteinSr proteinSNCG proteinBCSG1 proteinPERSYN proteinPRSN protein |
Information sourced from Uniprot.org