Function | Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake. |
Protein Name | Vesicular Inhibitory Amino Acid TransporterGaba And Glycine TransporterSolute Carrier Family 32 Member 1Vesicular Gaba TransporterHviaat |
Database Links | Reactome: R-HSA-425393Reactome: R-HSA-888590 |
Cellular Localisation | Cytoplasmic Vesicle MembraneMulti-Pass Membrane ProteinPresynapsePresents In Glycine-Gaba- Or Gaba- And Glycine-Containing Boutons |
Alternative Protein Names | Vesicular Inhibitory Amino Acid Transporter proteinGaba And Glycine Transporter proteinSolute Carrier Family 32 Member 1 proteinVesicular Gaba Transporter proteinHviaat proteinSLC32A1 proteinVGAT proteinVIAAT protein |
Information sourced from Uniprot.org