Human SLC32A1 protein (Recombinant) (N-GST & C-His) (STJP008827)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SLC32A1-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SLC32A1 |
| Gene ID | 140679 |
| Uniprot ID | VIAAT_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg30-Lys115 |
Additional Info
| Function | Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake. |
| Protein Name | Vesicular Inhibitory Amino Acid TransporterGaba And Glycine TransporterSolute Carrier Family 32 Member 1Vesicular Gaba TransporterHviaat |
| Database Links | Reactome: R-HSA-425393Reactome: R-HSA-888590 |
| Cellular Localisation | Cytoplasmic Vesicle MembraneMulti-Pass Membrane ProteinPresynapsePresents In Glycine-Gaba- Or Gaba- And Glycine-Containing Boutons |
| Alternative Protein Names | Vesicular Inhibitory Amino Acid Transporter proteinGaba And Glycine Transporter proteinSolute Carrier Family 32 Member 1 proteinVesicular Gaba Transporter proteinHviaat proteinSLC32A1 proteinVGAT proteinVIAAT protein |
Information sourced from Uniprot.org