Human SLC26A8 protein (Recombinant) (N-GST) (STJP005868)

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STJP005868
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLC26A8-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SLC26A8
Gene ID: 116369
Uniprot ID: S26A8_HUMAN
Immunogen Region: Thr664-Val970
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane. Stimulates anion transport activity of CFTR. May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation. May play a role in sperm tail differentiation and motility and hence male fertility.
Protein Name Testis Anion Transporter 1
Anion Exchange Transporter
Solute Carrier Family 26 Member 8
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Located At Both The Annulus And The Equatorial Segment Of The Human Sperm Head
Alternative Protein Names Testis Anion Transporter 1 protein
Anion Exchange Transporter protein
Solute Carrier Family 26 Member 8 protein
SLC26A8 protein
TAT1 protein

Information sourced from Uniprot.org

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