Human SKAP2 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007443)

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STJP007443
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SKAP2-N-His-SUMO & C-Strep protein was developed from e. coli and has a target region of N-His-SUMO & C-Strep. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SKAP2
Gene ID: 8935
Uniprot ID: SKAP2_HUMAN
Immunogen Region: Ala111-Glu222
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22.
Function May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
Protein Name Src Kinase-Associated Phosphoprotein 2
Pyk2/Raftk-Associated Protein
Retinoic Acid-Induced Protein 70
Skap55 Homolog
Skap-55hom
Skap-Hom
Src Family-Associated Phosphoprotein 2
Src Kinase-Associated Phosphoprotein 55-Related Protein
Src-Associated Adapter Protein With Ph And Sh3 Domains
Database Links Reactome: R-HSA-391160
Cellular Localisation Cytoplasm
Alternative Protein Names Src Kinase-Associated Phosphoprotein 2 protein
Pyk2/Raftk-Associated Protein protein
Retinoic Acid-Induced Protein 70 protein
Skap55 Homolog protein
Skap-55hom protein
Skap-Hom protein
Src Family-Associated Phosphoprotein 2 protein
Src Kinase-Associated Phosphoprotein 55-Related Protein protein
Src-Associated Adapter Protein With Ph And Sh3 Domains protein
SKAP2 protein
PRAP protein
RA70 protein
SAPS protein
SCAP2 protein
SKAP55R protein

Information sourced from Uniprot.org