• Human SIRP-beta-1/SIRPB1/CD172b protein (Recombinant) (C-His) (STJP001343)

Human SIRP-beta-1/SIRPB1/CD172b protein (Recombinant) (C-His) (STJP001343)

SKU:
STJP001343

£76.50 - £248.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human SIRP-beta-1/SIRPB1/CD172b-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Gene Symbol: SIRPB1
Gene ID: 10326
Uniprot ID: SIRB1_HUMAN
Immunogen: Recombinant Human SIRP-beta-1/SIRPB1/CD172b Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu30-Leu371) of human SIRPB1/CD172b (Accession #NP_006056.2) fused with a 6×His tag at the C-terminus.
Post Translational Modifications N-glycosylated.
Function Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Protein Name Signal-Regulatory Protein Beta-1
Sirp-Beta-1
Cd172 Antigen-Like Family Member B
Cd Antigen Cd172b
Database Links Reactome: R-HSA-2172127
Reactome: R-HSA-391160
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Signal-Regulatory Protein Beta-1 protein
Sirp-Beta-1 protein
Cd172 Antigen-Like Family Member B protein
Cd Antigen Cd172b protein
SIRPB1 protein

Information sourced from Uniprot.org

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