| Short Description : | Recombinant-Human SIAE-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | SIAE |
| Gene ID: | 54414 |
| Uniprot ID: | SIAE_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ala22-Pro244 |
| Function | Catalyzes the removal of O-acetyl ester groups from position 9 of the free diacetylated sialate N-acetyl-9-O-acetylneuraminate (Neu5,9Ac2) in the cytosol and of the diacetylated sialate residues of sialylglycoconjugates in the lysosomes (Probable). Together with the sialate-O-acetyltransferase they regulate the balance of acetylated sialoglycoconjugates, key players in various processes such as cell-cell interactions, host-pathogen recognition, and tumor antigenicity. |
| Protein Name | Sialate O-AcetylesteraseSiaeH-LseSialic Acid-Specific 9-O-Acetylesterase |
| Database Links | |
| Cellular Localisation | Isoform 1: LysosomeIsoform 2: Cytoplasm |
| Alternative Protein Names | Sialate O-Acetylesterase proteinSiae proteinH-Lse proteinSialic Acid-Specific 9-O-Acetylesterase proteinSIAE proteinYSG2 protein |
Information sourced from Uniprot.org