| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.01 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
APCS |
| Gene ID: |
325 |
| Uniprot ID: |
SAMP_HUMAN |
| Immunogen: |
Recombinant Human Serum Amyloid P/SAP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (His 20-Val 223) of human Serum Amyloid P (Accession #NP_001630.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: |
HTDLSGKVFVFPRESVTDHV NLITPLEKPLQNFTLCFRAY SDLSRAYSLFSYNTQGRDNE LLVYKERVGEYSLYIGRHKV TSKVIEKFPAPVHICVSWES SSGIAEFWINGTPLVKKGLR QGYFVEAQPKIVLGQEQDSY GGKFDRSQSFVGEIGDLYMW DSVLPPENILSAYQGTPLPA NILDWQALNYEIRGYVIIKP LVWV |
| Tissue Specificity | Found in serum and urine. |
| Post Translational Modifications | N-glycosylated with a complex biantennary oligosaccharide chain with a sialic acid at the end (disialo-SAP). Monosialo-SAP as well as asioalo-SAP are also detected. |
| Function | Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. |
| Protein Name | Serum Amyloid P-ComponentSap9.5s Alpha-1-Glycoprotein Cleaved Into - Serum Amyloid P-Component(1-203 |
| Database Links | Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Serum Amyloid P-Component proteinSap protein9.5s Alpha-1-Glycoprotein Cleaved Into - Serum Amyloid P-Component(1-203 proteinAPCS proteinPTX2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
