Human SERPINF1/PEDF/Serpin F1 protein (Recombinant-Active) (C-His) (STJP011982)

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STJP011982-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human SERPINF1/PEDF/Serpin F1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: SERPINF1
Gene ID: 5176
Uniprot ID: PEDF_HUMAN
Immunogen Region: Gln20-Pro418
Immunogen: Homo sapiens (Human)
Post Translational Modifications The N-terminus is blocked. Extracellular phosphorylation enhances antiangiogenic activity. N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
Function Neurotrophic protein.induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Protein Name Pigment Epithelium-Derived Factor
Pedf
Cell Proliferation-Inducing Gene 35 Protein
Epc-1
Serpin F1
Cellular Localisation Secreted
Melanosome
Enriched In Stage I Melanosomes
Alternative Protein Names Pigment Epithelium-Derived Factor protein
Pedf protein
Cell Proliferation-Inducing Gene 35 Protein protein
Epc-1 protein
Serpin F1 protein
SERPINF1 protein
PEDF protein
PIG35 protein

Information sourced from Uniprot.org

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