Human SEPTIN7 protein (Recombinant) (N-His) (STJP007439)

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STJP007439
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SEPTIN7-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SEPTIN7
Gene ID: 989
Uniprot ID: SEPT7_HUMAN
Immunogen Region: Gly32-Phe437
Immunogen: Homo sapiens (Human)
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
Protein Name Septin-7
Cdc10 Protein Homolog
Database Links Reactome: R-HSA-5687128
Cellular Localisation Cytoplasm
Chromosome
Centromere
Kinetochore
Cytoskeleton
Spindle
Cleavage Furrow
Midbody
Cilium Axoneme
Cell Projection
Cilium
Flagellum
Distributed Throughout The Cytoplasm In Prometaphase Cells
Associated With The Spindle During Metaphase
Associated With The Central Spindle And At The Cleavage Furrow In Anaphase Cells
Detected At The Midbody In Telophase
Associated With Actin Stress Fibers
Found In The Sperm Annulus
Alternative Protein Names Septin-7 protein
Cdc10 Protein Homolog protein
SEPTIN7 protein
CDC10 protein
SEPT7 protein

Information sourced from Uniprot.org

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