Function | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. |
Protein Name | Sec14-Like Protein 2Alpha-Tocopherol-Associated ProteinTapHtapSqualene Transfer ProteinSupernatant Protein FactorSpf |
Cellular Localisation | CytoplasmNucleusCytoplasmic In Absence Of Alpha-TocopherolAnd Nuclear In Presence Of Alpha-Tocopherol |
Alternative Protein Names | Sec14-Like Protein 2 proteinAlpha-Tocopherol-Associated Protein proteinTap proteinHtap proteinSqualene Transfer Protein proteinSupernatant Protein Factor proteinSpf proteinSEC14L2 proteinC22orf6 proteinKIAA1186 proteinKIAA1658 protein |
Information sourced from Uniprot.org