| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human SAP30-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | SAP30 |
| Gene ID: | 8819 |
| Uniprot ID: | SAP30_HUMAN |
| Immunogen Region: | Gln65-His220 |
| Immunogen: | Homo sapiens (Human) |
| Function | Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. (Microbial infection) Involved in transcriptional repression of HHV-1 genes TK and gC. |
| Protein Name | Histone Deacetylase Complex Subunit Sap3030 Kda Sin3-Associated PolypeptideSin3 Corepressor Complex Subunit Sap30Sin3-Associated Polypeptide P30 |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427413Reactome: R-HSA-9679191 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Histone Deacetylase Complex Subunit Sap30 protein30 Kda Sin3-Associated Polypeptide proteinSin3 Corepressor Complex Subunit Sap30 proteinSin3-Associated Polypeptide P30 proteinSAP30 protein |
Information sourced from Uniprot.org