Human ATP5MC1 protein (Recombinant) (N-His) (STJP014370)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ATP5MC1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for this information. |
Target Information
| Gene Symbol | ATP5MC1 |
| Gene ID | 516 |
| Uniprot ID | AT5G1_HUMAN |
| Immunogen | Human |
| Immunogen Region | Asp62-Met136 |
Additional Info
| Function | Subunit c, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). With the subunit a (MT-ATP6), forms the proton-conducting channel in the F(0) domain, that contains two crucial half-channels (inlet and outlet) that facilitate proton movement from the mitochondrial intermembrane space (IMS) into the matrix. Protons are taken up via the inlet half-channel and released through the outlet half-channel, following a Grotthuss mechanism. |
| Protein Name | Atp Synthase F(0 Complex Subunit C1 - MitochondrialAtp Synthase Lipid-Binding ProteinAtp Synthase Membrane Subunit C Locus 1Atp Synthase Proteolipid P1Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit C1Atpase Protein 9Atpase Subunit CProton-Conducting Channel - Atp Synthase F(0 Complex Subunit C |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Atp Synthase F(0 Complex Subunit C1 - Mitochondrial proteinAtp Synthase Lipid-Binding Protein proteinAtp Synthase Membrane Subunit C Locus 1 proteinAtp Synthase Proteolipid P1 proteinAtp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit C1 proteinAtpase Protein 9 proteinAtpase Subunit C proteinProton-Conducting Channel - Atp Synthase F(0 Complex Subunit C proteinATP5MC1 proteinATP5G1 protein |
Information sourced from Uniprot.org