SDS-PAGE gel of recombinant human RTN4IP1 protein under reducing conditions with Coomassie blue stain

Human RTN4IP1 protein (Recombinant) (His-Tag) (STJP017483)

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STJP017483
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Short Description :Recombinant-Human RTN4IP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% Glycerol, 0.1M NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:RTN4IP1
Gene ID:84816
Uniprot ID:RT4I1_HUMAN
Accession Number:NP_116119
Immunogen:Human
Immunogen Region:41-396aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSTVMPAWV IDKYGKNEVL RFTQNMMMPI IHYPNEVIVK VHAASVNPID VNMRSGYGAT ALNMKRDPLH VKIKGEEFPL TLGRDVSGVV MECGLDVKYF KPGDEVWAAV PPWKQGTLSE FVVVSGNEVS HKPKSLTHTQ AASLPYVALT AWSAINKVGG LNDKNCTGKR VLILGASGGV GTFAIQVMKA WDAHVTAVCS QDASELVR
Tissue Specificity Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta.
Function NAD(P)H oxidoreductase involved in the ubiquinone biosynthetic pathway. Required for the O-methyltransferase activity of COQ3. Able to catalyze the oxidoreduction of 3-demethylubiquinone into 3-demethylubiquinol in vitro. However, it is unclear if 3-demethylubiquinone constitutes a substrate in vivo. May also play a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury.
Protein Name Nad(Ph Oxidoreductase Rtn4ip1 - Mitochondrial
Nogo-Interacting Mitochondrial Protein
Reticulon-4-Interacting Protein 1
Database Links
Cellular Localisation Mitochondrion Matrix
Mitochondrion Outer Membrane
Mainly Localizes To The Mitochondrial Matrix
Also Colocalizes With The Endoplasmic Reticulum Hspa5 At Spots Corresponding To Contacts With Mitochondria
Alternative Protein Names Nad(Ph Oxidoreductase Rtn4ip1 - Mitochondrial protein
Nogo-Interacting Mitochondrial Protein protein
Reticulon-4-Interacting Protein 1 protein
RTN4IP1 protein
NIMP protein

Information sourced from Uniprot.org

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