Human Renin/REN protein (Recombinant) (C-His) (STJP001191)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Renin/REN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu24-Arg406) of human Renin (Accession #NP_000528.1.) fused with a 8×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Renin/REN-C-His protein was developed in hek293 cells using the region Leu24-Arg406. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. Immobilized Human REN Protein at 0.5 Mu g/mL (100 Mu L/well) can bind Renin Rabbit pAb with a linear range of 1.9-302.7 ng/mL. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | REN |
| Gene ID | 5972 |
| Uniprot ID | RENI_HUMAN |
| Immunogen | Recombinant Human Renin/REN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu24-Arg406) of human Renin (Accession #NP_000528.1.) fused with a 8×His tag at the C-terminus. |
| Immunogen Region | Leu24-Arg406 |
| Immunogen Sequence | LPTDTTTFKRIFLKRMPSIR ESLKERGVDMARLGPEWSQP MKRLTLGNTTSSVILTNYMD TQYYGEIGIGTPPQTFKVVF DTGSSNVWVPSSKCSRLYTA CVYHKLFDASDSSSYKHNGT ELTLRYSTGTVSGFLSQDII TVGGITVTQMFGEVTEMPAL PFMLAEFDGVVGMGFIEQAI GRVTPIFDNIISQGVLKEDV FSFYYNRDSENSQSLGGQIV LGGSDPQHYEGNFHYINLI |
Additional Info
| Protein Name | ReninAngiotensinogenase |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | SecretedMembraneAssociated To Membranes Via Binding To Atp6ap2 |
| Alternative Protein Names | Renin proteinAngiotensinogenase proteinREN protein |
Information sourced from Uniprot.org