| Short Description : | Recombinant-Human Renin/REN-C-His protein was developed in hek293 cells using the region Leu24-Arg406. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human REN Protein at 0.5 Mu g/mL (100 Mu L/well) can bind Renin Rabbit pAb with a linear range of 1.9-302.7 ng/mL. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | REN |
| Gene ID: | 5972 |
| Uniprot ID: | RENI_HUMAN |
| Immunogen: | Recombinant Human Renin/REN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu24-Arg406) of human Renin (Accession #NP_000528.1.) fused with a 8×His tag at the C-terminus. |
| Immunogen Region: | Leu24-Arg406 |
| Immunogen Sequence: | LPTDTTTFKRIFLKRMPSIR ESLKERGVDMARLGPEWSQP MKRLTLGNTTSSVILTNYMD TQYYGEIGIGTPPQTFKVVF DTGSSNVWVPSSKCSRLYTA CVYHKLFDASDSSSYKHNGT ELTLRYSTGTVSGFLSQDII TVGGITVTQMFGEVTEMPAL PFMLAEFDGVVGMGFIEQAI GRVTPIFDNIISQGVLKEDV FSFYYNRDSENSQSLGGQIV LGGSDPQHYEGNFHYINLI |
| Protein Name | ReninAngiotensinogenase |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | SecretedMembraneAssociated To Membranes Via Binding To Atp6ap2 |
| Alternative Protein Names | Renin proteinAngiotensinogenase proteinREN protein |
Information sourced from Uniprot.org
