Human Reg4 protein (Recombinant) (T7-Tag) (STJP019077)

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STJP019077
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Reg4-T7-Tag protein was developed from e.coli and has a target region of T7-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: REG4
Gene ID: 83998
Uniprot ID: REG4_HUMAN
Immunogen Region: 23-158aa
Accession Number: NP_114433
Immunogen: Human
Immunogen Sequence: DIIM RPSCAPGWFY HKSNCYGYFR KLRNWSDAEL ECQSYGNGAH LASILSLKEA STIAEYISGY QRSQPIWIGL HDPQKRQQWQ WIDGAMYLYR SWSGKSMGGN KHCAEMSSNN NFLTWSSNEC NKRQHFLCKY RP
Tissue Specificity Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
Function Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
Protein Name Regenerating Islet-Derived Protein 4
Reg-4
Gastrointestinal Secretory Protein
Reg-Like Protein
Regenerating Islet-Derived Protein Iv
Reg Iv
Database Links
Cellular Localisation Secreted
Alternative Protein Names Regenerating Islet-Derived Protein 4 protein
Reg-4 protein
Gastrointestinal Secretory Protein protein
Reg-Like Protein protein
Regenerating Islet-Derived Protein Iv protein
Reg Iv protein
REG4 protein
GISP protein
RELP protein

Information sourced from Uniprot.org

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