Human RASA1 protein (Recombinant) (N-His) (STJP004303)

SKU:
STJP004303
£328.50 - £1,437.50
Free Shipping
Processing The item has been added

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RASA1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RASA1
Gene ID: 5921
Uniprot ID: RASA1_HUMAN
Immunogen Region: Pro403-Leu596
Immunogen: Homo sapiens (Human)
Post Translational Modifications The N-terminus is blocked. Phosphorylated by SRC and LCK. The phosphorylation SRC inhibits its ability to stimulate the Ras-GTPase activity, whereas phosphorylation by LCK does not display any effect on stimulation activity.
Function Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21.this stimulation may be further increased in the presence of NCK1.
Protein Name Ras Gtpase-Activating Protein 1
Gap
Gtpase-Activating Protein
Rasgap
Ras P21 Protein Activator
P120gap
Database Links Reactome: R-HSA-186763
Reactome: R-HSA-3928662
Reactome: R-HSA-5218921
Reactome: R-HSA-5658442
Reactome: R-HSA-8849471
Cellular Localisation Cytoplasm
Alternative Protein Names Ras Gtpase-Activating Protein 1 protein
Gap protein
Gtpase-Activating Protein protein
Rasgap protein
Ras P21 Protein Activator protein
P120gap protein
RASA1 protein
GAP protein
RASA protein

Information sourced from Uniprot.org