| Short Description : | Recombinant-Human RAB27B-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | RAB27B |
| Gene ID: | 5874 |
| Uniprot ID: | RB27B_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Met1-Asp196 |
| Function | Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes. |
| Protein Name | Ras-Related Protein Rab-27bC25kg |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
| Cellular Localisation | MembraneLipid-AnchorLate Endosome |
| Alternative Protein Names | Ras-Related Protein Rab-27b proteinC25kg proteinRAB27B protein |
Information sourced from Uniprot.org