Human RAB27B protein (Recombinant) (N-His) (STJP007379)

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STJP007379
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RAB27B-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RAB27B
Gene ID: 5874
Uniprot ID: RB27B_HUMAN
Immunogen Region: Met1-Asp196
Immunogen: Homo sapiens (Human)
Function Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes.
Protein Name Ras-Related Protein Rab-27b
C25kg
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-8873719
Reactome: R-HSA-8876198
Cellular Localisation Membrane
Lipid-Anchor
Late Endosome
Alternative Protein Names Ras-Related Protein Rab-27b protein
C25kg protein
RAB27B protein

Information sourced from Uniprot.org