Function | Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes. |
Protein Name | Ras-Related Protein Rab-27bC25kg |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
Cellular Localisation | MembraneLipid-AnchorLate Endosome |
Alternative Protein Names | Ras-Related Protein Rab-27b proteinC25kg proteinRAB27B protein |
Information sourced from Uniprot.org