Human POU2AF1 protein (Recombinant) (N-His-KSI) (STJP015949)

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STJP015949
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human POU2AF1-N-His-KSI protein was developed from e.coli and has a target region of N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: POU2AF1
Gene ID: 5450
Uniprot ID: OBF1_HUMAN
Immunogen Region: Leu2-Phe256
Immunogen: Homo sapiens (Human)
Post Translational Modifications Ubiquitinated.mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
Function Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator.
Protein Name Pou Domain Class 2-Associating Factor 1
B-Cell-Specific Coactivator Obf-1
Bob-1
Oca-B
Oct-Binding Factor 1
Database Links
Cellular Localisation Nucleus
Alternative Protein Names Pou Domain Class 2-Associating Factor 1 protein
B-Cell-Specific Coactivator Obf-1 protein
Bob-1 protein
Oca-B protein
Oct-Binding Factor 1 protein
POU2AF1 protein
BOB1 protein
OBF1 protein

Information sourced from Uniprot.org

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