Human PNPLA3 (Patatin Like Phospholipase Domain Containing Protein 3) Sandwich ELISA Kit Kit (STJE0011581)

Human PNPLA3 (Patatin Like Phospholipase Domain Containing Protein 3) Sandwich ELISA Kit Kit (STJE0011581)

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STJE0011581
£465.50 - £636.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.29ng/mL
Detection Limit: 0.781-50ng/mL
Short Description : This PNPLA3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: PNPLA3
Gene ID: 80339
Uniprot ID: PLPL3_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety. However, the triacylglycerol hydrolase activity is controversial and may be very low. Possesses phospholipase A2 activity.
Protein Name 1-Acylglycerol-3-Phosphate O-Acyltransferase Pnpla3
Acylglycerol Transacylase
Adiponutrin
Adpn
Calcium-Independent Phospholipase A2-Epsilon
Ipla2-Epsilon
Lysophosphatidic Acid Acyltransferase
Patatin-Like Phospholipase Domain-Containing Protein 3
Database Links Reactome: R-HSA-1482883
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Lipid Droplet
Alternative ELISA Names 1-Acylglycerol-3-Phosphate O-Acyltransferase Pnpla3 ELISA kit
Acylglycerol Transacylase ELISA kit
Adiponutrin ELISA kit
Adpn ELISA kit
Calcium-Independent Phospholipase A2-Epsilon ELISA kit
Ipla2-Epsilon ELISA kit
Lysophosphatidic Acid Acyltransferase ELISA kit
Patatin-Like Phospholipase Domain-Containing Protein 3 ELISA kit
PNPLA3 ELISA kit
ADPN ELISA kit
C22orf20 ELISA kit
output

Information sourced from Uniprot.org

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