Human PADI6 protein (Recombinant) (N-GST & C-His) (STJP016051)

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STJP016051
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PADI6-N-GST & C-His protein was developed from e.coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: PADI6
Gene ID: 353238
Uniprot ID: PADI6_HUMAN
Immunogen Region: Val2-Pro694
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylation at Ser-10, possibly by RSK-type kinases, and Ser-446 creates binding sites for 14-3-3 proteins.
Function Structural constituent of cytoplasmic lattices, which plays a key role in early embryonic development. Cytoplasmic lattices consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos. They are required to store maternal proteins critical for embryonic development, such as ribosomal proteins and proteins that control epigenetic reprogramming of the preimplantation embryo, and prevent their degradation or activation. In contrast to other members of the family, does not show protein-arginine deiminase activity due to its inability to bind Ca(2+).
Protein Name Inactive Protein-Arginine Deiminase Type-6
Peptidyl Arginine Deiminase-Like Protein
Peptidylarginine Deiminase Vi
Hpadvi
Protein-Arginine Deiminase Type Vi
Protein-Arginine Deiminase Type-6
Database Links Reactome: R-HSA-3247509
Cellular Localisation Cytoplasm
Cytoplasmic Vesicle
Secretory Vesicle
Cortical Granule
Nucleus
Core Component Of Cytoplasmic Lattices In Oocytes
Also Nuclear
Alternative Protein Names Inactive Protein-Arginine Deiminase Type-6 protein
Peptidyl Arginine Deiminase-Like Protein protein
Peptidylarginine Deiminase Vi protein
Hpadvi protein
Protein-Arginine Deiminase Type Vi protein
Protein-Arginine Deiminase Type-6 protein
PADI6 protein
PAD6 protein

Information sourced from Uniprot.org