Human P-Selectin/CD62P protein (Recombinant) (C-His-Avi) {Biotin} (STJP001544)

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STJP001544
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Short Description :Recombinant-Human P-Selectin/CD62P-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Host:HEK293
Note:STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Biotin
Dilution Range:Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Formulation:Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Storage Instruction:The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin:Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol:SELP
Gene ID:6403
Uniprot ID:LYAM3_HUMAN
Immunogen:DNA sequence encoding Human P-Selectin/CD62P including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Immunogen Region:Trp42-Ala771
Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3).
Protein Name P-Selectin
Cd62 Antigen-Like Family Member P
Granule Membrane Protein 140
Gmp-140
Leukocyte-Endothelial Cell Adhesion Molecule 3
Lecam3
Platelet Activation Dependent Granule-External Membrane Protein
Padgem
Cd Antigen Cd62p
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names P-Selectin protein
Cd62 Antigen-Like Family Member P protein
Granule Membrane Protein 140 protein
Gmp-140 protein
Leukocyte-Endothelial Cell Adhesion Molecule 3 protein
Lecam3 protein
Platelet Activation Dependent Granule-External Membrane Protein protein
Padgem protein
Cd Antigen Cd62p protein
SELP protein
GMRP protein
GRMP protein

Information sourced from Uniprot.org