• Biotinylated Human P-Selectin on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human P-Selectin is greater than 95% as determined by SEC-HPLC.
  • Immobilized Anti-P-selectin Antibody, hFc Tag at 0. 5 Mu g/ml (100 Mu l/Well) on the plate. Dose response curve for Biotinylated Human P-Selectin, His Tag with the EC50 of 0. 11 Mu g/ml determined by ELISA.

Human P-Selectin/CD62P protein (Recombinant) (C-His-Avi) {Biotin} (STJP001544)

SKU:
STJP001544

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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human P-Selectin/CD62P-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: SELP
Gene ID: 6403
Uniprot ID: LYAM3_HUMAN
Immunogen Region: Trp42-Ala771
Immunogen: DNA sequence encoding Human P-Selectin/CD62P including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
Protein Name P-Selectin
Cd62 Antigen-Like Family Member P
Granule Membrane Protein 140
Gmp-140
Leukocyte-Endothelial Cell Adhesion Molecule 3
Lecam3
Platelet Activation Dependent Granule-External Membrane Protein
Padgem
Cd Antigen Cd62p
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names P-Selectin protein
Cd62 Antigen-Like Family Member P protein
Granule Membrane Protein 140 protein
Gmp-140 protein
Leukocyte-Endothelial Cell Adhesion Molecule 3 protein
Lecam3 protein
Platelet Activation Dependent Granule-External Membrane Protein protein
Padgem protein
Cd Antigen Cd62p protein
SELP protein
GMRP protein
GRMP protein

Information sourced from Uniprot.org

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