Human Otubain-2/OTUB2 protein (Recombinant) (His-Tag) (STJP017174)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Otubain-2/OTUB2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 50mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OTUB2 |
| Gene ID | 78990 |
| Uniprot ID | OTUB2_HUMAN |
| Accession Number | NP_075601 |
| Immunogen | Human |
| Immunogen Region | 1-234aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Widely expressed. Expressed at higher level in brain. |
| Function | Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains. |
| Protein Name | Ubiquitin Thioesterase Otub2Deubiquitinating Enzyme Otub2Otu Domain-Containing Ubiquitin Aldehyde-Binding Protein 2Otubain-2Ubiquitin-Specific-Processing Protease Otub2 |
| Database Links | Reactome: R-HSA-5689896 |
| Cellular Localisation | |
| Alternative Protein Names | Ubiquitin Thioesterase Otub2 proteinDeubiquitinating Enzyme Otub2 proteinOtu Domain-Containing Ubiquitin Aldehyde-Binding Protein 2 proteinOtubain-2 proteinUbiquitin-Specific-Processing Protease Otub2 proteinOTUB2 proteinC14orf137 proteinOTB2 proteinOTU2 protein |
Information sourced from Uniprot.org