| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Osteoactivin/GPNMB-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Immunoreactivity: |
Measured by its binding ability in a functional ELISA. Immobilized Human GPNMB Protein at 1 Mu g/mL (100 Mu L/well) can bind GPNMB Rabbit pAb with a linear range of 0.976-116.5 ng/mL. |
| Gene Symbol: |
GPNMB |
| Gene ID: |
10457 |
| Uniprot ID: |
GPNMB_HUMAN |
| Immunogen: |
Recombinant Human Osteoactivin/GPNMB Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro474) of human Osteoactivin/GPNMB (Accession #NP_002501.1) fused with a 6×His tag at the C-terminus. |
| Function | Could be a melanogenic enzyme. |
| Protein Name | Transmembrane Glycoprotein NmbHematopoietic Growth Factor Inducible Neurokinin-1 Type |
| Database Links | Reactome: R-HSA-8857538 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinMelanosome MembraneEarly Endosome MembraneIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Protein Names | Transmembrane Glycoprotein Nmb proteinHematopoietic Growth Factor Inducible Neurokinin-1 Type proteinGPNMB proteinHGFIN proteinNMB proteinUNQ1725 proteinPRO9925 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
