| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human NBL1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to inhibit BMP-4-induced activity in mouse preosteoblast cells (MC3T3‑E1). The ED50 for this effect is 0.2-1 µg/mL in the presence of 50 ng/mL of rhBMP-4. |
| Gene Symbol: | NBL1 |
| Gene ID: | 100532736/4681 |
| Uniprot ID: | NBL1_HUMAN |
| Immunogen Region: | Ala17-Asp181 |
| Immunogen: | Homo sapiens (Human) |
| Function | Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process. |
| Protein Name | Neuroblastoma Suppressor Of Tumorigenicity 1Dan Domain Family Member 1Protein N03Zinc Finger Protein Dan |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Neuroblastoma Suppressor Of Tumorigenicity 1 proteinDan Domain Family Member 1 proteinProtein N03 proteinZinc Finger Protein Dan proteinNBL1 proteinDAN proteinDAND1 protein |
Information sourced from Uniprot.org
