Human MYL12B protein (Recombinant) (His-Tag) (STJP017687)

SKU:
STJP017687
£134.50 - £738.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MYL12B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% Glycerol, 2mM DTT
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: MYL12B
Gene ID: 103910
Uniprot ID: ML12B_HUMAN
Immunogen Region: 1-172aa
Accession Number: NP_001138417
Immunogen: Human
Immunogen Sequence: MSSKKA KTKTTKKRPQ RATSNVFAMF DQSQIQEFKE AFNMIDQNRD GFIDKEDLHD MLASLGKNPT DAYLDAMMNE APGPINFTMF LTMFGEKLNG TDPEDVIRNA FACFDEEATG TIQEDYLREL LTTMGDRFTD EEVDELYREA PIDKKGNFNY IEFTRILKHG AKDKDD
Tissue Specificity Ubiquitously expressed in various hematopoietic cells.
Post Translational Modifications Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge. Phosphorylation is reduced following epigallocatechin-3-O-gallate treatment.
Function Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.
Protein Name Myosin Regulatory Light Chain 12b
Mlc-2a
Mlc-2
Myosin Regulatory Light Chain 2-B - Smooth Muscle Isoform
Myosin Regulatory Light Chain 20 Kda
Mlc20
Myosin Regulatory Light Chain Mrlc2
Shujun-1
Database Links Reactome: R-HSA-3928663
Reactome: R-HSA-416572
Reactome: R-HSA-445355
Reactome: R-HSA-5625740
Reactome: R-HSA-5625900
Reactome: R-HSA-5627117
Reactome: R-HSA-5627123
Cellular Localisation
Alternative Protein Names Myosin Regulatory Light Chain 12b protein
Mlc-2a protein
Mlc-2 protein
Myosin Regulatory Light Chain 2-B - Smooth Muscle Isoform protein
Myosin Regulatory Light Chain 20 Kda protein
Mlc20 protein
Myosin Regulatory Light Chain Mrlc2 protein
Shujun-1 protein
MYL12B protein
MRLC2 protein
MYLC2B protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP003211 Human MYL12B protein (Recombinant) (N-His) (STJP003211) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP018040 Human MVK protein (Recombinant) (His-Tag) (STJP018040) E.coli SDS-PAGE
STJP018054 Human MAVS protein (Recombinant) (His-Tag) (STJP018054) E.coli SDS-PAGE
STJP018052 Human DEDD protein (Recombinant) (His-Tag) (STJP018052) E.coli SDS-PAGE/Denatured
STJP018049 Human PIP4K2B protein (Recombinant) (His-Tag) (STJP018049) E.coli SDS-PAGE

Related Products

!