Human MYDGF/SF20 protein (Recombinant-Active) (C-His) (STJP012222)

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STJP012222-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human MYDGF/SF20-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: MYDGF
Gene ID: 56005
Uniprot ID: MYDGF_HUMAN
Immunogen Region: Val32-Leu173
Immunogen: Homo sapiens (Human)
Function Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
Protein Name Myeloid-Derived Growth Factor
Mydgf
Database Links Reactome: R-HSA-381038
Cellular Localisation Secreted
Endoplasmic Reticulum-Golgi Intermediate Compartment
Endoplasmic Reticulum
Golgi Apparatus
The C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum
Alternative Protein Names Myeloid-Derived Growth Factor protein
Mydgf protein
MYDGF protein
C19orf10 protein

Information sourced from Uniprot.org

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