Name: Human MYDGF protein (Recombinant) (C-His) (STJP001958)
SKU: STJP001958
Availability: InStock

Human MYDGF protein (Recombinant) (C-His) (STJP001958)

SKU:

STJP001958

£97.50 - £291.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 0.1 EU/Mu g

Gene Symbol:	MYDGF
Gene ID:	56005
Uniprot ID:	MYDGF_HUMAN
Immunogen Region:	Val32-Leu173
Immunogen:	Recombinant Human MYDGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val32-Leu173) of human MYDGF (Accession #NP_061980.1) fused with a 6×His tag at the C-terminus.
Immunogen Sequence:	VSEPTTVAFDVRPGGVVHSF SHNVGPGDKYTCMFTYASQG GTNEQWQMSLGTSEDHQHFT CTIWRPQGKSYLYFTQFKAE VRGAEIEYAMAYSKAAFERE SDVPLKTEEFEVTKTAVAHR PGAFKAELSKLVIVAKASRT EL

Function	Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
Protein Name	Myeloid-Derived Growth Factor Mydgf
Database Links	Reactome: R-HSA-381038
Cellular Localisation	Secreted Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum Golgi Apparatus The C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum
Alternative Protein Names	Myeloid-Derived Growth Factor protein Mydgf protein MYDGF protein C19orf10 protein

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJP001984	Mouse MYDGF protein (Recombinant) (C-His) (STJP001984)	HEK293 cells
STJP002835	Human CD63 protein (Recombinant) (C-His) (STJP002835)	HEK293 cells

Human MYDGF protein (Recombinant) (C-His) (STJP001958)