• Human MYBPC3 (Myosin-binding protein C, cardiac-type) CLIA Kit (STJC0000374)

Human MYBPC3 (Myosin-binding protein C, cardiac-type) CLIA Kit (STJC0000374)

SKU:
STJC0000374

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Applications: CLIA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 18.75pg/mL
Detection Limit: 31.25~2000pg/mL
Short Description: This human MYBPC3 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: MYBPC3
Gene ID: 4607
Uniprot ID: MYPC3_HUMAN
Specificity: This kit recognizes Human MYBPC3 in samples. No significant cross-reactivity or interference between Human MYBPC3 and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Post Translational Modifications Substrate for phosphorylation by PKA and PKC. Reversible phosphorylation appears to modulate contraction. Polyubiquitinated.
Function Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Protein Name Myosin-Binding Protein C - Cardiac-Type
Cardiac Mybp-C
C-Protein - Cardiac Muscle Isoform
Database Links Reactome: R-HSA-390522
Alternative CLIA Names Myosin-Binding Protein C - Cardiac-Type CLIA kit
Cardiac Mybp-C CLIA kit
C-Protein - Cardiac Muscle Isoform CLIA kit
MYBPC3 CLIA kit
Specificity This kit recognizes Human MYBPC3 in samples. No significant cross-reactivity or interference between Human MYBPC3 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 86-97 92
EDTA plasma(n=8) 97-111 103
Cell culture media(n=8) 95-112 102

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (pg/mL) 104.54 184.96 687.68 99.78 180.80 704.40
Standard deviation 10.20 15.48 72.21 9.47 16.25 60.44
CV (%) 9.76 8.37 10.50 9.49 8.99 8.58
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance